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A thin-section study of the morphogenesis of Aujeszky's disease virus in synchronously infected cell cultures



A thin-section study of the morphogenesis of Aujeszky's disease virus in synchronously infected cell cultures



Archiv fur die gesamte Virusforschung 34(3): 189-201



Morphogenesis of the virus in synchronously infected pig kidney cells was studied at hourly intervals for 24 hours. Naked capsids were present in the nucleus from 3 hours and in the cytoplasm from 4 hours after infection. Capsids acquired their envelope not only at the inner nuclear membrane but also in the cytoplasm at smooth-membraned vesicles, the outer nuclear membrane, rough endoplasmic reticulum or the Golgi complex. Extracellular mature virus first appeared at 5 hours and after this time most enveloped particles were extracellular. Virus was probably released by fusion of vesicles with the plasma membrane.

Accession: 000011482

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PMID: 4107354

DOI: 10.1007/bf01242992

Download PDF Full Text: A thin-section study of the morphogenesis of Aujeszky's disease virus in synchronously infected cell cultures



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