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Effects of the epidermal chalone on DNA synthesis in mammalian epidermal cells


Journal of Investigative Dermatology 60: 160-165
Effects of the epidermal chalone on DNA synthesis in mammalian epidermal cells
The rate of incorporation of tritiated thymidine (3H-TdR) was used to measure the synthetic capabilities of pig epidermal cells in vitro in the presence of ethanolie fractions of a tissue-specific mitotic inhibitor (chalone). In control cultures, a synthetic lag period of approx. two hrs was followed by a period of maximal DNA synthesis at 4 hrs incubation.


Accession: 000081088



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