Section 1
Chapter 84

Enhancement of iron absorption from ligated segments of rat intestine by histidine, cysteine, and lysine: effects of removing ionizing groups and of stereoisomerism

Van Campen, D.

Journal of Nutrition 103(1): 139-142


ISSN/ISBN: 0022-3166
PMID: 4682447
DOI: 10.1093/jn/103.1.139
Accession: 000083582

The effectiveness of L-histidine, L-cysteine and L-lysine in increasing Fe uptake from ligated segments of duodenum in vivo was compared with that of several structurally similar compounds from which ionizing groups had been removed. Decarboxylation of histidine, removal of the epsilon -amino of lysine and the substitution of a hydrogen or hydroxyl group for the sulphydryl of cysteine all resulted in a loss of their ability to increase Fe uptake.

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