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High pathogenicity for mice by mouth of a viral component of the ERA/BMK modified live-virus rabies vaccine. Vaccinal prophylaxis of rabies in France



High pathogenicity for mice by mouth of a viral component of the ERA/BMK modified live-virus rabies vaccine. Vaccinal prophylaxis of rabies in France



Bulletin de l' Academie Veterinaire de France 47(8/9): 423-435



Rabies vaccine strain ERA was derived from a canine street virus, passed in series intracerebrally for years through mice, then adapted to tissue culture. The vaccine ERA/BHK was purified on Vero cells by the plaque method; it is about 1000 times more virulent than the standard fixed virus strain of the Pasteur Institute.

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