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Mites and house dust allergy. III. In vitro lymphocyte transformation and precipitating antibody to house dust and mite (Dermatophagoides pteronyssinus) extract in atopic and non-atopic individuals



Mites and house dust allergy. III. In vitro lymphocyte transformation and precipitating antibody to house dust and mite (Dermatophagoides pteronyssinus) extract in atopic and non-atopic individuals



Clinical Allergy 3(1): 51-56



Studies were made of in vitro lymphocyte transformation and the precipitating antibody to extracts of house dust and Dermatophagoides pteronyssinus (Trt.) in patients sensitive to mites and to house dust and in non-atopic individuals. House-dust extract was able to induce a marked incorporation of thymidine labelled with 14C into lymphocytes from patients sensitive to house dust as well as those from non-allergic individuals. An in vitro response to mite extract, even if less marked, was also seen in most patients sensitive to mites. By the micro-Ouchterlony and counterimmunoelectrophoresis techniques, antibodies to dust were found in the serum of all patients sensitive to house dust and non-atopic individuals. Precipitins against mites were detected in a smaller number of subjects.

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Accession: 000139163

Download citation: RISBibTeXText

PMID: 4632865

DOI: 10.1111/j.1365-2222.1973.tb01309.x


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