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Pathological changes caused by experimental trypanosomiasis in mice, rats, and guinea-pigs


Pathological changes caused by experimental trypanosomiasis in mice, rats, and guinea-pigs



Trudy Uzbekskogo Nauchno issledovatel' skogo Veterinarnogo Institut 20: 70-72



Thirty mice, 20 rats, and 10 guinea-pigs were infected with the camel trypanosome, Trypanosoma ninaekohljakimovi. Mice and rats were given 0.5 ml i/v, guinea pigs 1 ml s/c. In mice, trypanosomes appeared in peripheral blood on the 2nd day, in rats on the 4th day, and in guinea-pigs on the 10th. Mice were most severely affected, clinical signs were loss of appetite, drowsiness, photophobia; and later blindness, paralysis of hind legs and emaciation.

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Accession: 000156805

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