Thirty mice, 20 rats, and 10 guinea-pigs were infected with the camel trypanosome, Trypanosoma ninaekohljakimovi. Mice and rats were given 0.5 ml i/v, guinea pigs 1 ml s/c. In mice, trypanosomes appeared in peripheral blood on the 2nd day, in rats on the 4th day, and in guinea-pigs on the 10th. Mice were most severely affected, clinical signs were loss of appetite, drowsiness, photophobia; and later blindness, paralysis of hind legs and emaciation.