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Studies on passive immunity in the foal. 1. Gamma-globulin and antibody variations associated with the maternal transfer of immunity and the onset of active immunity

Studies on passive immunity in the foal. 1. Gamma-globulin and antibody variations associated with the maternal transfer of immunity and the onset of active immunity

Journal of Comparative Pathology 84(1): 93-101

Serum protein patterns in mares before and after foaling were examined. A fall in serum globulins, particularly gamma-globulin, detected about 2 weeks before parturition, was attributed to selective concentration by the mammary gland of immune proteins and specific antibody from the blood for colostrum formation. After parturition the levels of protein and antibody in colostrum fell rapidly as the foal was suckled, and by 12 to 15 hours they were only 10-20% of their original concentration.

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Accession: 000205229

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PMID: 4137211

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