+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Toxicological and pharmacological relations between levamisole, pyrantel and diethylcarbamazine and their significance in helminth chemotherapy



Toxicological and pharmacological relations between levamisole, pyrantel and diethylcarbamazine and their significance in helminth chemotherapy



Southeast Asian Journal of Tropical Medicine and Public Health 3(2): 235-241



The effects of levamisole hydrochloride, pyrantel tartrate, morantel tartrate and diethylcarbamazine citrate were studied in the anaesthetized dog. All the drugs caused a precipitous pressor response and an enhancement of rate and depth of respiration. These effects were antagonized by hexamethonium and the pressor responses were nullified by the adrenergic blocking agent, phentolamine.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 000252117

Download citation: RISBibTeXText

PMID: 5082852


Related references

Comparative activity of pyrantel tartrate, parbendazole, and levamisole at two dose levels against naturally acquired helminth infections in sheep. Journal of Parasitology 57(5): 1078-1082, 1971

Chemotherapy with diethylcarbamazine and levamisole in Bancroftian filariasis. Tropenmedizin und Parasitologie 32(4): 250-252, 1981

Chemotherapy of onchocerciasis: a controlled comparison of mebendazole, levamisole, and diethylcarbamazine. Lancet 2(8245): 485-490, 1981

Canine and human toxocariasis and its chemotherapy with ivermectin, pyrantel pamoate and levamisole hydrochloride. Proceedings of Pakistan Congress of Zoology 15: 217-222, 1995

Chemotherapy with spaced doses of diethylcarbamazine preceded by levamisole in Bancroftian filariasis. Transactions of the Royal Society of Tropical Medicine and Hygiene5(6): 835-837, 1981

Onchocerciasis chemotherapy. II. Evaluation of two therapeutic schemes on microfilarial density, utilising the association diethylcarbamazine and levamisole. Medecine Tropicale 39(6): 631-635, 1979

The anthelmintic effects of pyrantel pamoate, oxantel-pyrantel pamoate, levamisole and mebendazole in the treatment of intestinal nematodes. Annals of Tropical Medicine and Parasitology 75(3): 315-321, 1981

Actions of potent cholinergic anthelmintics (morantel, pyrantel and levamisole) on an identified insect neurone reveal pharmacological differences between nematode and insect acetylcholine receptors. Neuropharmacology 27(8): 843-848, 1988

Comparative efficacy of diethylcarbamazine, albendazole and a combination of diethylcarbamazine and albendazole in clearance of multiple helminth infections, Kwale District, Kenya. American Journal of Tropical Medicine & Hygiene 61(3 Suppl. ): 444-445, 1999

Comparison of albendazole and levamisole chemotherapy on prevalence and intensity of common soil-transmitted helminth infections in school children, Sierra Leone. West African Journal of Medicine 16(3): 179-183, 1997

Metabolic activation of marihuana constituents: relations to pharmacological and toxicological effects. Yakugaku Zasshi 106(7): 537-561, 1986

Nanoparticles: pharmacological and toxicological significance. British Journal of Pharmacology 150(5): 552-558, 2007

Resistance to levamisole and cross-resistance between pyrantel and levamisole in Oesophagostomum quadrispinulatum and Oesophagostomum dentatum of pigs. Veterinary Parasitology 37(1): 21-30, 1990

Resistance to pyrantel and levamisole in oesophagostomum spp of pigs. Israel Journal of Entomology (87): 393-395, 1991

The significance of the "lung phase" in host-helminth relations. Parassitologia 34(1-3): 23-30, 1992