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Toxicological and pharmacological relations between levamisole, pyrantel and diethylcarbamazine and their significance in helminth chemotherapy

Toxicological and pharmacological relations between levamisole, pyrantel and diethylcarbamazine and their significance in helminth chemotherapy

Southeast Asian Journal of Tropical Medicine and Public Health 3(2): 235-241

The effects of levamisole hydrochloride, pyrantel tartrate, morantel tartrate and diethylcarbamazine citrate were studied in the anaesthetized dog. All the drugs caused a precipitous pressor response and an enhancement of rate and depth of respiration. These effects were antagonized by hexamethonium and the pressor responses were nullified by the adrenergic blocking agent, phentolamine.

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Accession: 000252117

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PMID: 5082852

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