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Effective treatment of Trypanosoma vivax infections with salicylhydroxamic acid (SHAM)

Effective treatment of Trypanosoma vivax infections with salicylhydroxamic acid (SHAM)

Transactions of the Royal Society of Tropical Medicine and Hygiene 72(2): 203-204

Swiss T.O. mice were infected with the Y486 strain of Trypanosoma vivax and treated with salicylhydroxamic acid 430 mg/kg plus glycerol 3.6 g/kg, intraperitoneally, subcutaneously or orally. This cured them (as judged by 2 months observation). A dose of 171 mg/kg depressed the Trypanosome count only temporarily.

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Accession: 000358957

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PMID: 653794

DOI: 10.1016/0035-9203(78)90065-2

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