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Histopathologic and electron microscopic studies of cutaneous lesions in calves with experimentally induced East Coast fever (theileriosis)



Histopathologic and electron microscopic studies of cutaneous lesions in calves with experimentally induced East Coast fever (theileriosis)



American Journal of Veterinary Research 39(7): 1117-1122



Skin lesions of bovine East Coast Fever were examined by light and electron microscopy 120 hours after attachment of Rhipicephalus appendiculatus ticks infected with Theileria parva. The lesions included epidermal ulcer, haemorrhage, oedema, necrosis and inflammatory cell infiltration by mostly polymorphonuclear and mononuclear (lymphoid) cells. The trophozoite stage of T. parva was observed in a parasitophorous vacuole and feeding on neutrophil granules. Schizonts, some in budding process, and merozoites were extracellular and among many mononuclear phagocytes (lymphoid cells). Some merozoites were seen in mononuclear phagocytes and a granulocyte. Some of the cells had already transformed into lymphoblasts with pseudopodia. [AS].

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Accession: 000396343

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PMID: 98077



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