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Hydrogen cyanide detoxification by Gloeocercospora sorghi

Hydrogen cyanide detoxification by Gloeocercospora sorghi

Physiological Plant Pathology 7(1): 23-33

G. sorghi, the cause of zonate leaf spot of sorghum, is adaptively tolerant of HCN. Associated with adaptation to HCN is the appearance of formamide hydro-lyase. The enzyme is induced by HCN and converts HCN to formamide, a relatively nontoxic compound. Formamide hydro-lyase from G. sorghi has characteristics of a high mol. wt. enzyme, is stable during storage at 4 deg C, has opt. activity at pH 7-9, and has a Km of c. 30 mM HCN.

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Accession: 000398439

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DOI: 10.1016/0048-4059(75)90056-9

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