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Mel B toxicity in human trypanosomiasis in the Gboko endemic area of Nigeria

Mel B toxicity in human trypanosomiasis in the Gboko endemic area of Nigeria

Acta Tropica 33(1): 96-100

The authors describe 9 patients who developed toxic symptoms due to melarsoprol treatment for sleeping sickness. 2 patients (who had convulsions) died. The symptoms in the other patients consisted mostly of pyrexia, vomiting or diarrhoea. The treatment consists of 3.6 mg/kg body-weight given intravenously for 3 to 4 days followed by a 2nd (or 3rd) course after 7 to 14 days.

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Accession: 000428446

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PMID: 13638

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