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Mutagenic action of ascorbic acid



Mutagenic action of ascorbic acid



Nature, UK 260(5553): 722-724



Evidence for the mutagenic action of ascorbic acid was obtained and the results of changes in cultured human fibroblasts after treatment with a mixture of ascorbic acid and divalent Cu are reported. DNA fragmentation, occurrence of DNA repair, estimated from the rate of uptake of hymidine in nondividing cell populations, and chromosome breakages were observed.

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Accession: 000436476

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