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Passive immunization against transmissible gastroenteritis virus in piglets by ingestion of milk of sows inoculated with attenuated virus



Passive immunization against transmissible gastroenteritis virus in piglets by ingestion of milk of sows inoculated with attenuated virus



National Institute of Animal Health Quarterly 18(2): 43-52



Groups of 10-20 pregnant sows were inoculated with a low-titre live virus vaccine (prepared from the attenuated strain TO-163) by 2 of 3 routes, intramuscular (i.m.) intranasal (i.n.) or oral, 2 months and 2 wk resp. before farrowing. Neutralizing antibody titres in colostrum and milk between 3 and 9 days after farrowing were highest in sows given 107 50%-tissue-culture-infective-dose (TCID50) units i.m. at 2 months and 107 units i.n. at 2 wk.

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Accession: 000453224

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PMID: 211443


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