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Physiological differences between fertilized and unfertilized mouse ova: glycerol permeability and freezing sensitivity

Physiological differences between fertilized and unfertilized mouse ova: glycerol permeability and freezing sensitivity

Dissertation Abstracts International, B 38(2): 466

In female mice given HCG, the times of ovulation, fertilisation and 1st cleavage were 11-16, 12-18 and 30-34 h following HCG resp. The coefficients of permeability to glycerol and their temp.-dependence were measured for fertilised and unfertilised mouse ova. At approx. 20 deg , 12 deg and 3 deg C, fertilisation caused significant increases in glycerol permeability. The increase was gradual, rather than large and instantaneous.

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Accession: 000458565

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