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Possible relationship of levels of mucosal IgA and serum IgG to immune unresponsiveness of lambs to Haemonchus contortus


Possible relationship of levels of mucosal IgA and serum IgG to immune unresponsiveness of lambs to Haemonchus contortus



Veterinary Parasitology 4(1): 21-27



ISSN/ISBN: 0304-4017

DOI: 10.1016/0304-4017(78)90032-8

Abomasal mucus IgA and serum IgG antibodies were studied in adult sheep and young lambs vaccinated with irradiated Haemonchus contortus larvae and subsequently challenged with normal larvae. In the adult sheep, protection against challenge was associated with raised levels of these antibodies. Vaccination of the lambs, on the other hand, did not protect against challenge nor did it stimulate either serum IgG or mucus IgA antibodies.

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Accession: 000463430

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