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Regulation of blood pyridoxal phosphate in riboflavin deficiency in man

Regulation of blood pyridoxal phosphate in riboflavin deficiency in man

Nutrition and Metabolism 20(4): 228-233

ISSN/ISBN: 0029-6678

PMID: 1029812

Synthesis and breakdown of pyridoxal phospahte by erythrocytes were studied in subjects with oral lesions before and after treatment with riboflavin. In vivo conversion of pyridoxine to pyridoxal phosphate and in vitro synthesis of pyridoxal phosphate by erythrocytes were lower in subjects with lesions of the mouth and improved markedly after treatment with riboflavin. Erythrocyte phosphatase activity, with pyridoxal phosphate as substrate, was lower in riboflavin-deficient subjects and showed an increase after treatment with riboflavin.

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Accession: 000479644

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