EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Resistance to infection with Schistosoma mansoni after immunization with worm extracts or live cercariae: role of cytotoxic antibody in mice and guinea pigs



Resistance to infection with Schistosoma mansoni after immunization with worm extracts or live cercariae: role of cytotoxic antibody in mice and guinea pigs



American Journal of Tropical Medicine and Hygiene 24(6 Pt 1): 955-962



Mice and guinea-pigs were immunized with adult and cercarial extracts of Schistosoma mansoni prepared in different ways. Most animals responded by producing moderate to high levels of cytotoxic antibody, but no correlation with resistance to infection could be detected. Initial experiments with a 3M KCl adult extract and with cercarial exoantigen produced partial resistance; several attempts to reproduce those results failed.

(PDF emailed within 1 workday: $29.90)

Accession: 000485107

Download citation: RISBibTeXText

PMID: 1200260



Related references

Schistosoma mansoni resistance to an infection with cercariae induced by the transfer of live adult worms to the rat. International Journal for Parasitology 10(1): 13-20, 1980

Immunization of baboons against schistosoma mansoni using irradiated schistosoma mansoni cercariae and schistosomula and nonirradiated schistosoma rodhaini cercariae. Journal of Helminthology 50(3): 215-221, 1976

Schistosoma mansoni: the attrition of a challenge infection in mice immunized with highly irradiated live cercariae. Experimental Parasitology 50(2): 212-221, 1980

Autoradiographic study of the attrition of migrating schistosomula in the skin of mice ii. mice challenged with normal schistosoma mansoni cercariae after immunization with highly irradiated cercariae. Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College 5(1): 30-36, 1990

Schistosoma mansoni: analysis of the humoral and cellular basis of resistance in guinea-pigs vaccinated with radiation-attenuated cercariae. Parasitology 100 Pt 1: 35-44, 1990

Site potential for challenge attrition in mice, rats and guinea pigs vaccinated with irradiated cercariae of Schistosoma mansoni. Parasite Immunology 7(1): 29-44, 1985

Localized skin changes at the site of immunization with highly irradiated cercariae of Schistosoma mansoni are associated with enhanced resistance to a challenge infection. Parasitology 85: 305-314, 1982

Schistosoma mansoni: influence of immunization and challenge schedules on the sites and mechanisms of resistance in CBA/Ca mice vaccinated with highly irradiated cercariae. Journal of Helminthology 63(3): 173-190, 1989

Schistosoma mansoni--NZ rabbit-model: resistance due to infection and active immunization with adult worm antigen. Memorias do Instituto Oswaldo Cruz 82 Suppl 4: 233-233, 1987

Splenic cytokine mRNA expression in mice intravenously injected with Schistosoma mansoni 26-kDa glutathione S-transferase or soluble egg antigen before infection with Schistosoma mansoni cercariae. Egyptian Journal of Bilharziasis 1999; 19: 1-21, 1997

Host-parasite relationships in schistosomiasis. I. The effect of temperature on the infection of Biomphalaria sudanica tanganyicensis with Schistosoma mansoni miracidia and of laboratory mice with Schistosoma mansoni cercariae. Annals of Tropical Medicine and Parasitology 60(1): 90-93, 1966

The host parasite relationship between the saudi arabian schistosoma mansoni and its intermediate and definitive hosts 2. effects of temperature salinity and ph on the infection of mice by schistosoma mansoni cercariae. Southeast Asian Journal of Tropical Medicine and Public Health 18(2): 166-170, 1987

Surface antigen detected by a Schistosoma mansoni monoclonal antibody in worm extracts and kidney deposits of infected mice and hamsters. Infection and Immunity 52(1): 230-235, 1986

Immunization of mice and baboons with the recombinant Sm28GST affects both worm viability and fecundity after experimental infection with Schistosoma mansoni. Parasite Immunology 13(5): 473-490, 1991

Resistance to challenge infection in immuno deficient mice vaccinated with irradiated cercariae of schistosoma mansoni. Federation Proceedings 41(3): ABSTRACT 1817, 1982