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Respiration of hydrogenosomes of Tritrichomonas foetus. II. Effect of CoA on pyruvate oxidation



Respiration of hydrogenosomes of Tritrichomonas foetus. II. Effect of CoA on pyruvate oxidation



Journal of Biological Chemistry 253(4): 1215-1218



In broken hydrogenosomes of Tritrichomonas foetus, pyruvate-supported respiration is greatly enhanced by coenzyme A. Additions of small amounts of CoA result in a phenomenon resembling respiratory control. ADP and GDP also have a stimulatory effect but the primary controlling factor of pyruvate oxidation is probably the availability of CoA as acetyl acceptor.

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Accession: 000485300

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PMID: 624726



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