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Response of calf to parenteral administration of cyclophosphamide



Response of calf to parenteral administration of cyclophosphamide



Archiv fur Experimentelle Veterinarmedizin 31(1): 29-51



Pneumonia or enteritis developed in calves a few days after a single injection of cyclophosphamide at 50 mg/kg or more, and death ensued within one or two weeks. The initial leukocyte response was an increase of neutrophilic granulocytes and decrease in lymphocytes. After the initial increase in granulocytes they disappeared almost completely from the circulation. In surviving calves the leukocyte values took several weeks to return to normal.

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Accession: 000485548

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