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Response of falciparum malaria to a standard regimen of chloroquine in Vientiane, Lao People's Democratic Republic



Response of falciparum malaria to a standard regimen of chloroquine in Vientiane, Lao People's Democratic Republic



Journal of Tropical Medicine and Hygiene 80(12): 230-237



In and near Vientiane, Lao People's Democratic Republic, chloroquine at 25 mg base/kg body-weight was given over 3 days to 48 people who were asymptomatic or had mild to moderate symptoms of malaria. 15 still had asexual parasitaemia 7 days after treatment; 3 of these had been negative for 24 to 72 hours and 2 of the remaining 12 had a higher parasite density 7 days after treatment than before. 10 other were still positive although the parasite density was much lower than it had been before treatment. Of 32 cases from Vientiane, 5 had no trophozoites on day 7 but returned with mild fever and low level asexual parasitaemia within 2 weeks of the end of the test period.

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Accession: 000485648

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PMID: 342718



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