+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Response of plasma insulin to small doses of tolbutamide in obesity and acromegaly

Response of plasma insulin to small doses of tolbutamide in obesity and acromegaly

International Journal of Obesity 1(4): 315-324

The early response of plasma insulin (IRI) to successive intravenous doses of 50, 100 and 200 mg tolbutamide was studied in nondiabetic obese subjects, in acromegalic patients and in healthy controls. The smallest dose increased plasma IRI within 2 min in all subjects. The insulin response was correlated with basal IRI in controls and in obese subjects but not in acromegalic patients. At each tolbutamide dose the mean IRI response of obese subjects was about 3 times that in controls.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 000485829

Download citation: RISBibTeXText

PMID: 617112

Related references

Plasma insulin response to small doses of intra venous tolbutamide in obesity. Acta Endocrinologica Supplementum 190:, 1974

Plasma insulin response to small doses of intra venous glucose and to tolbutamide in obesity. Diabetologia 7(5): 397-398, 1971

Early response of plasma insulin to small doses of intravenous glucose: effect of obesity. Journal of Clinical Endocrinology and Metabolism 39(3): 418-424, 1974

Estimation of insulin efficacy in obesity by the response of blood insulin and glucose to intravenous tolbutamide. Annales d'Endocrinologie 27(6): 820-829, 1966

Dynamics of tolbutamide glucose and insulin interrelationship following varying doses of oral tolbutamide. Indian Journal of Pharmacology 14(1): 95-96, 1982

Dynamics of tolbutamide, glucose, and insulin interrelationships following varying doses of intravenous tolbutamide in normal subjects. Diabetes 24(4): 354-367, 1975

A comparison of the influence of tolbutamide and small doses of insulin on the splanchnic output and peripheral uptake of glucose in man. Annals of the new York Academy of Sciences 74(3): 537-547, 1959

Oral antidiabetics as substitutes for small insulin doses in psychiatric patients. A clinical trial with chlorpropamide and tolbutamide. Nordisk Medicin 64: 1002-1005, 1960

Hyper insulin response to oral leucine in obesity and acromegaly. Clinical Research:, 1972

Tolbutamide tolerance test and plasma-insulin response in hypoglycemia. Journal of Pediatrics 72(4): 557-560, 1968

Serum immunoreactive insulin response to oral glucose and intravenous sodium tolbutamide administration in relation to obesity. Israel Journal of Medical Sciences 8(6): 815-820, 1972

Diurnal variation in the blood-sugar and plasma-insulin response to tolbutamide. Lancet ii(7784): 945-947, 1972

Blood sugar and plasma insulin response to tolbutamide in the morning and afternoon. Diabetologia 9(1): 73, 1973

Tolbutamide tolerance test and plasma-insulin response in children with idiopathic hypoglycemia. Journal of Pediatrics 71(4): 485-493, 1967

The plasma insulin response to glucose and tolbutamide in mild juvenile diabetes mellitus. Butterfield, W J H And W Van Westering (Edited By) International Congress Series No 149 Tolbutamide After Ten Years Proceedings Of The Brook Lodge Symposium, Augusta, Mich , March 6-7, Vi + 346p Illus Excerpta Medica Foundation: New York, N Y , U S A ; Paper 255-260, 1967