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Carbohydrate and sucrose intake in the causation of atherosclerotic heart disease, diabetes mellitus, and dental caries



Carbohydrate and sucrose intake in the causation of atherosclerotic heart disease, diabetes mellitus, and dental caries



American Journal of Clinical Nutrition 32(12 Suppl.): 2644-2647



The associations between dietary carbohydrate and coronary heart disease (CHD), diabetes mellitus, and dental caries are examined. The kinds of evidence reviewed include the epidemiological and animal and human experiments. In humans, no long-term effects of high-carbohydrate or sucrose diets on CHD have been shown, and no studies of high-sucrose intake in relation to diabetes mellitus have been performed. However, individuals fed high sucrose foods develop a higher incidence of dental caries. The quality and strength of the evidence are examined regarding consistency among various populations and among individuals in a given population, as well as autopsy data, strength of association, animal models, and biological explanations. Regarding the risks and benefits of reducing carbohydrate intake, the possible benefits of a high-carbohydrate, low-fat diet have never been directly tested in terms of atherosclerotic disease, but only in terms of plasma lipid levels. No risks or benefits to diabetes mellitus have been demonstrated for variations in intake of sucrose or other carbohydrates. Reduction of sucrose consumption results in decreased dental caries without known risk.

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Accession: 000609638

Download citation: RISBibTeXText

PMID: 506984

DOI: 10.1093/ajcn/32.12.2644


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