Direct activation by histamine of the carbonic anhydrase in the human gastric mucosa

Puscas, I.; Buzas, G.; Contrasiu, P.; Suranyi, P.

Revue Roumaine de Biochimie 16(4): 317-320

1979


Accession: 000632500

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Abstract
Carbonate dehydratase in parietal cells from gastric mucosa of 24 patients with duodenal ulcer increased when histamine 0.1 ml of a 45 X 10-5 M solution was added to the incubation medium. Activity also increased in vivo in the same patients when they were given histamine 0.04 mg/kg bodyweight.