Home
  >  
Section 1
  >  
Chapter 640

Effect of falciparum malaria infection on the in vitro mitogen responses of spleen and peripheral blood lymphocytes from owl monkeys

Taylor, D.W.; Siddiqui, W.A.

American Journal of Tropical Medicine and Hygiene 27(4): 738-742

1978

ISSN/ISBN: 0002-9637
PMID: 99058
Accession: 000639891
Download citation:  
Text
  |  
BibTeX
  |  
RIS
In 12 Aotus trivirgatus monkeys infected at less than 25% parasitaemia with Plasmodium falciparum Vietnam-Oak Knoll strain (FVO), the response of blood lymphocytes (PBL) to mitogen stimulation was normal; but if the parasitaemia was greater than 25% the response to Concanavalin A (Con A) was depressed. A suppression of responsiveness to Con A was also seen in 8 monkeys infected with the Uganda-Palo Alto strain but at 10 to 25% parasitaemia.

PDF emailed within 1 workday: $29.90




Related References

Modzelewski, R.A.; Conner, M.K. 1990: Disparate cytogenetic responses of peripheral blood and spleen lymphocytes to ethenoadenine nucleotides in vitro; maximal expression in splenic lymphocytes under conditions of enhanced membrane permeabilization Carcinogenesis 11(4): 571-576
Mitsuya, H.; Osaki, K.; Tomino, S.; Katsuki, T.; Kishimoto, S. 1981: Pathophysiologic analysis of peripheral blood lymphocytes from patients with primary immunodeficiency. I. Ig synthesis by peripheral blood lymphocytes stimulated with either pokeweed mitogen or Epstein-Barr virus in vitro Journal of Immunology 127(1): 311-315
Tajima, M.; Fujinaga, T.; Okamoto, Y.; Otomo, K.; Koike, T. 1990: Relationship between mitogen receptors in peripheral blood lymphocytes and blastogenic responses to mitogen Research in Veterinary Science 48(1): 1-5
Kanai, K.; Kato, K.; Sano, H.; Nagata, K.; Okuno, K.; Kuwamoto, S.; Higaki, H.; Sugihara, H.; Kato, M.; Murakami, I.; Hayashi, K. 2011: In vitro Epstein-Barr virus infection model of rabbit lymphocytes from peripheral blood or spleen Intervirology 54(1): 17-24
Taylor, D.W.; Crum, S.R.; Kramer, K.J.; Siddiqui, W.A. 1980: Alterations in the distribution and proliferative responses of rhesus monkey peripheral blood and spleen cells during malaria (Plasmodium knowlesi) infection Infection and Immunity 28(2): 502-507
Begara, I.L.jan, L.C.llie, D.; Miller, H.; Watt, N. 1995: In vitro response of lymphocytes from bronchoalveolar lavage fluid and peripheral blood to mitogen stimulation during natural maedi-visna infection Veterinary immunology and immunopathology 49(1-2): 75-88
Begara, I.; Luján, L.; Collie, D.S.; Miller, H.R.; Watt, N.J. 1995: In vitro response of lymphocytes from bronchoalveolar lavage fluid and peripheral blood to mitogen stimulation during natural maedi-visna virus infection Veterinary Immunology and Immunopathology 49(1-2): 75-88
Chen, C.H.; Campbell, P.A.; Newman, L.S. 1990: MTT colorimetric assay detects mitogen responses of spleen but not blood lymphocytes International Archives of Allergy and Applied Immunology 93(2-3): 249-255
Carvalho, L.H.; Fontes, C.J.F.; Krettli, A.U. 1992: Peripheral blood mononuclear cells from human malaria In vitro responses to circumsporozoite protein of Plasmodium vivax and Plasmodium falciparum Memorias do Instituto Oswaldo Cruz Rio de Janeiro 87(Suppl 2): 257
Ashman, R.B.; Nahmias, A.J. 1978: Effect of incubation temperature on mitogen responses of lymphocytes from adult peripheral blood and from cord blood Clinical and Experimental Immunology 33(2): 319-326
Michelis, F.V.; Delitheos, A.K.; Tiligada, E. 2013: Seasonal influence on mitogen and cyclosporin responses of peripheral blood lymphocytes International Immunopharmacology 16(2): 154-159
Hirahara, F.; Gorai, I.; Kusaba, T.; Sumiyoshi, Y.; Minaguchi, H.; Nakauchi, H. 1985: The role of peripheral blood T and B lymphocytes in mitogen responses during human pregnancy Journal of Clinical and Laboratory Immunology 16(4): 191-195
Sieber, G.; Enders, B.; Wegscheider, K.; Ruehl, H. 1982: In vitro modulation of spontaneous and pokeweed mitogen induced immuno globulin production of human peripheral blood lymphocytes by pre incubated autologous and hla typed allogeneic lymphocytes Immunobiology 162(4-5): 422-423
Michelis, F.V.; Delitheos, A.; Tiligada, E. 2011: Molybdate modulates mitogen and cyclosporin responses of human peripheral blood lymphocytes Journal of Trace Elements in Medicine and Biology: Organ of the Society for Minerals and Trace Elements 25(3): 138-142
Rumley, R.L.; Chapman, S.W.; Hoover, M.L.; Cuchens, M.A. 1984: Effects of different protein supplements on mitogen responses of human peripheral blood lymphocytes Journal of Immunological Methods 75(2): 339-349
Troye-Blomberg, M.; Sjöholm, P.E.; Perlmann, H.; Patarroyo, M.E.; Perlmann, P. 1983: Regulation of the immune response in Plasmodium falciparum malaria. I. Non-specific proliferative responses in vitro and characterization of lymphocytes Clinical and Experimental Immunology 53(2): 335-344
Cavanagh, D.R.; Kocken, C.H.M.; White, J.H.; Cowan, G.J.M.; Samuel, K.; Dubbeld, M.A.; Voorberg-van der Wel, A.; Thomas, A.W.; McBride, J.S.; Arnot, D.E. 2014: Antibody responses to a novel Plasmodium falciparum merozoite surface protein vaccine correlate with protection against experimental malaria infection in Aotus monkeys Plos one 9(1): E83704
DeGuise, S.; Bernier, J.; Dufresne, M.M.; Martineau, D.; Beland, P.; Fournier, M. 1996: Immune functions in beluga whales (Delphinapterus leucas): evaluation of mitogen-induced blastic transformation of lymphocytes from peripheral blood, spleen and thymus Veterinary Immunology and Immunopathology 50(1-2): 117-126
Kuronuma, T. 1981: Sub population and mitogen responses of peripheral blood lymphocytes in idiopathic nephrotic syndrome in childhood Hirosaki Medical Journal 33(1): 129-143
Chessin, L.N.; Börjeson, J.; Welsh, P.D.; Douglas, S.D.; Cooper, H.L. 1966: Studies on human peripheral blood lymphocytes in vitro. II. Morphological and biochemical studies on the transformation of lymphocytes by pokeweed mitogen Journal of Experimental Medicine 124(5): 873-884