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Hitch-hiking and linkage disequilibrium: the example of two closely linked loci in the pig, halothane sensitivity (Hal) and phosphohexose isomerase (PHI)



Hitch-hiking and linkage disequilibrium: the example of two closely linked loci in the pig, halothane sensitivity (Hal) and phosphohexose isomerase (PHI)



Paper, 30th Annual Meeting, European Association for Animal Production (G6.1): 4



Two Pietrain lines were selected for an index combining av. daily gain and backfat thickness (line PA) and for a visual score of muscle development (PB). Data on 465 pigs from the 3rd and 4th generations of this experiment indicated significant linkage disequilibrium for Hal and PHI in line PA but not line PB. The allele Hals (halothane sensitivity) is favoured in selection for muscle development, whereas PHI appears to be selectively neutral.

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Accession: 000673674

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Related references

The "hitch-hiking" effect of a selected gene and gamete combination (linkage disequilibrium): the example of 2 closely linked loci in the swine, Hal (halothane sensitivity) and PHI (phosphohexose isomerase). Comptes Rendus des Seances de L'academie des Sciences. Serie D, Sciences Naturelles 289(2): 153-156, 1979

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