Section 1
Chapter 677

Immune mechanisms against canine distemper. II. Role of antibody in antigen modulation and prevention of intercellular and extracellular spread of canine distemper virus

Ho, C.K.; Babiuk, L.A.

Immunology 38(4): 765-772


ISSN/ISBN: 0019-2805
PMID: 118114
Accession: 000676312

Specific antibody was highly effective in neutralizing extracellular canine distemper virus (CDV) as well as preventing its intercellular spread. Thus, relatively low levels of antibody neutralized 1 X 105 TCID50 of extracellular CDV, and the development of plaques or CPE in Hep-2 and Vero cells respectively could be prevented even when up to 5% of the cells were infected.

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