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Studies on in vitro antimicrobial activity of miconazole. III. Further studies on anti-Candida action



Studies on in vitro antimicrobial activity of miconazole. III. Further studies on anti-Candida action



Japanese Journal of Medical Mycology 20(1): 20-30



Miconazole was cidal and static against Candida albicans in comparison with clostrimazole which was static. Miconazole was more active against cells in the exponential growth phase than those in the initial growth phase whilst clotrimazole behaved almost uniformly throughout all growth. Both antimycotics exhibited a more potent cidal activity on the resting conidia of Trichophyton mentagrophytes at their higher concs. At lower concs. miconazole was less effective than clotrimazole.

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