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Studies on specific and non-specific factors involved in experimental Candida albicans infection of mice, with particular reference to spleen lymphocytes

Studies on specific and non-specific factors involved in experimental Candida albicans infection of mice, with particular reference to spleen lymphocytes

Japanese Journal of Medical Mycology 19(3): 185-192

Results showed that nonspecific resistance of mice against infections with either of 2 C. albicans strs. was not affected by genetic controls. Sublethal irradiation or cyclophosphamide administration enhanced the susceptibility of mice to infection with the highly virulent str. Immunization with living cells of the highly virulent str. markedly protected cyclophosphamide-treated mice against infection with the same str.

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Accession: 000756619

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DOI: 10.3314/jjmm1960.19.185

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