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Antigenic and biological relationships between human coronavirus OC43 and neonatal calf diarrhoea coronavirus



Antigenic and biological relationships between human coronavirus OC43 and neonatal calf diarrhoea coronavirus



Journal of General Virology 54(Pt 1): 91-102



Monospecific antisera were prepared in mice to human coronavirus OC43 and neonatal calf diarrhoea coronavirus (NCDCV) which had been previously adapted to growth in suckling mouse brain. Brain suspension from infected suckling mice was used as immunogen. The antigenic relationship between OC43 and NCDCV was studied by the indirect immunoperoxidase antibody technique, by the haemagglutination-inhibition (HI) test and a new infectious centre-reduction neutralization test.

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Accession: 000823237

Download citation: RISBibTeXText

PMID: 6169790

DOI: 10.1099/0022-1317-54-1-91


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