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Assessment of 35972 RP (oltipraz) a new antischistosomal drug against Schistosoma haematobium, Schistosoma mansoni, and Schistosoma intercalatum

Assessment of 35972 RP (oltipraz) a new antischistosomal drug against Schistosoma haematobium, Schistosoma mansoni, and Schistosoma intercalatum

Acta Tropica 37(3): 271-274

Oltipraz (35972 RP) was given to 116 patients infected with Schistosoma haematobium in Mali, to 72 with S. intercalatum in Gabon and to 47 with S. mansoni and 86 with S. haematobium in Paris, France. Judging by faecal or urine egg counts, all cases of S. mansoni were cured by a total dose of 3 to 5 g over 2 to 5 days, and 87% of the cases of S. intercalatum were cured by a total dose of 1.25 to 4.50 g over 3 days.

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Accession: 000825432

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PMID: 6106367

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