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Coordination of protein synthesis and degradation



Coordination of protein synthesis and degradation



Ciba Foundation Symposium 75: (Protein degradation in health and disease) 253-272



Studies by the authors on synthesis and degradation of proteins in rat liver and rat mammary gland are summarized and discussed. These studies show that rate of degradation and synthesis of mammary fatty acid synthetase is dependent on the presence or absence of hormones (insulin, prolactin and cortisol), whereas the increase in casein synthesis which occurs in the presence of hormones continues at a reduced rate when they are removed, and casein is not degraded but secreted.

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Accession: 000848465

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