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Host defense mechanisms against nematode parasites: destruction of newborn Trichinella spiralis larvae by human antibodies and granulocytes



Host defense mechanisms against nematode parasites: destruction of newborn Trichinella spiralis larvae by human antibodies and granulocytes



Journal of Infectious Diseases 143(5): 712-718



Trichinella spiralis newborn larvae, muscle-stage larvae and adults were incubated in vitro with human leukocytes from normal human donors in the presence of serum from infected people and complement. Eosinophils and, to a lesser extent, neutrophils attached to the newborn larvae and exerted a cytotoxic effect manifested as complete morphological destruction; monocytes also attached to newborn larvae but did not mediate parasite destruction.

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Accession: 000903089

Download citation: RISBibTeXText

PMID: 7017021

DOI: 10.2307/30113292



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