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Human lymphocyte-activating properties of a purified polysaccharide from Candida albicans: B and T cell cooperation in the mitogenic response



Human lymphocyte-activating properties of a purified polysaccharide from Candida albicans: B and T cell cooperation in the mitogenic response



Journal of Immunology 125(5): 2082-2088



Neither T nor B cells alone could respond to a purified polysaccharide (MPPS) extracted from C. albicans. When a mixture of these 2 cell types was tested, a normal response (comparable to the one of unfractionated peripheral blood lymphocytes) was observed. This response was not affected by prior depletion of macrophages.

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Accession: 000903671

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PMID: 7000896



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