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Labon-gur (common salt and brown sugar) oral rehydration solution in the treatment of diarrhoea in adults

Labon-gur (common salt and brown sugar) oral rehydration solution in the treatment of diarrhoea in adults

Journal of Tropical Medicine and Hygiene 83(1): 41-45

A clinical trial to observe the efficacy of an oral solution containing common salt (labon) and unrefined sugar (gur) was conducted on 50 adult patients in Dacca, Bangladesh, with moderate dehydration due to diarrhea of varying etiology. Failure was defined as not correcting initial dehydration, not maintaining hydration or developing an electrolyte imbalance at any time during the study period. Volume loss was corrected in less than 8 h by drinking the labon-gur solution. Acidosis (CO2 < 20 meq/l) was not corrected in 20% of patients even after 48 h of therapy. The severity and persistence of acidosis was significantly correlated with the stool volume. Adult patients with diarrhea and dehydration are readily rehydrated, if they drink a simple salt-sugar solution. When fluid losses exceed 50 ml/kg per 24 h acidosis will not be corrected for several days. The failure to correct acidosis promptly may not be of great clinical importance in adults with mild diarrhea, and in such cases sodium bicarbonate may not be needed. More serious consequences of sustained acidosis may result in children and severely affected adults. This requires further evaluation.

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Accession: 000919480

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PMID: 7365864

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