EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Resistance and susceptibility of mice to bacterial infection. IV. Genetic and cellular basis of resistance to chronic infection with Brucella abortus



Resistance and susceptibility of mice to bacterial infection. IV. Genetic and cellular basis of resistance to chronic infection with Brucella abortus



Journal of Infectious Diseases 146(3): 381-387



The number of Brucella abortus strain 19 organisms in the spleens of CBA/H mice peaked two weeks after intravenous injection of 5 X 105 organisms. With the onset of specific cell-mediated immunity, 90% of the bacteria were killed, but about a million bacteria persisted up to seven weeks after infection. In contrast, in BALB/c, C57BL/10, and B10Br mice, bacterial numbers peaked at two weeks but decreased steadily with the onset of bactericidal activity.

(PDF emailed within 0-6 h: $19.90)

Accession: 000969680

Download citation: RISBibTeXText

PMID: 6809847

DOI: 10.1093/infdis/146.3.381



Related references

Comparison of brucella abortus and brucella melitensis infection of mice and their effect on acquired cellular resistance. Clinical Research: 772a, 1978

Genetic and cellular basis of susceptibility or resistance to Friend leukemia virus infection in mice. Proceedings. Canadian Cancer Conference 8: 313-343, 1969

Immunization of Mice with Recombinant Brucella abortus Organic Hydroperoxide Resistance (Ohr) Protein Protects Against a Virulent Brucella abortus 544 Infection. Journal of Microbiology and Biotechnology 26(1): 190-196, 2016

Cellular resistance to bacterial infection. 3. Modifications of the resistance of NCS mice to infection by Listeria monocytogenes after endotoxin injection. Comparative effects of an endotoxin injection and an active immunization on the morphological aspect and cellular resistance to infection of the macrophages of NCS mice. Annales de L'institut Pasteur 110(3): Suppl:95-105, 1966

Cellular resistance to bacterial infection. IV. Active immunization and resistance of the macrophages of NCS mice to the intracellular multiplication of Listeria monocytogenes, Corynebacterium kutscheri and Brucella melitensis. Annales de L'institut Pasteur 110(3): Suppl:106-17, 1966

AIM2 senses Brucella abortus DNA in dendritic cells to induce IL-1β secretion, pyroptosis and resistance to bacterial infection in mice. Microbes and Infection: -, 2018

Resistance and susceptibility of mice to bacterial infection 4. functional specificity in natural resistance to facultative intra cellular bacteria. Journal of the Reticuloendothelial Society 34(4): 299-310, 1983

Development of Brucella abortus, Brucella melitensis and Brucella and Brucella suis infection infection in mice to a chronic stage and cure. Annales de Recherches Veterinaires. Annals of Veterinary Research 13(2): 153-161, 1982

Resistance of mice, immunized by killed brucella to intravenous, intraperitoneal or sub-cutaneous infection with Brucella abortus. 1980

Cellular resistance to bacterial infection- IIIVariations of host resistance to Listeria infection in endotoxin treated mice. 1966

Cellular-resistance to infection IV Active immunization and cellular resistance to infection with Listeria monocytogess, corynebacterium kutscheri and Brucella melitensis. 1966

Induced resistance of mice to infection with Brucella abortus 2308 through vaccination with BCG. Nature 182(4639): 883-884, 1958

Induced resistance of mice to infection with Brucella abortus 2308 through vaccination with BCG. Nature. Lond., 182: 883-884, 1958

Interferon Induction and Resistance to Virus Infection in Mice Infected with Brucella abortus. Infection and Immunity 2(6): 698-704, 1970

(T)0interference of coxiella burneti infection in mice with nonspecific resistance or immunity against challenge with brucella abortus. 1969