EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Resistance to Echinococcus granulosus infection in lambs



Resistance to Echinococcus granulosus infection in lambs



Journal of Parasitology 67(6): 797-799



A high level of resistance of oral infection with Echinococcus granulosus eggs was stimulated in lambs by two or more subcutaneous injections of oncospheres given 14 days apart. The degree of resistance was significantly higher than that resulting from a single injection. Resistance was apparently stimulated by the activated oncosphere or a stage of cyst development prior to 14 days of age. Studies on oncospheres cultured in vitro in sera collected from animals during immunization or after oral challenge showed that most cysts were killed before 7 days of culture had elapsed. This confirmed the observation that resistance was stimulated by an early stage of cyst development. The in vitro test also showed that two injections of oncospheres resulted in a marked increase in the lethal effects of serum. These lethal effects decreased with time, providing circumstantial evidence that the high degree of resistance stimulated by two or more injections may only be transient.

(PDF emailed within 0-6 h: $19.90)

Accession: 000969952

Download citation: RISBibTeXText

PMID: 7328452

DOI: 10.2307/3280702



Related references

First molecular evidence of the simultaneous human infection with two species of Echinococcus granulosus sensu lato: Echinococcus granulosus sensu stricto and Echinococcus canadensis. Parasitology Research 115(3): 1065-1069, 2016

Identification of protein components of echinococcus granulosus protoscolex antigens for specific serodiagnosis of echinococcus granulosus infection in dogs. Parasite Immunology (Oxford) 11(3): 279-292, 1989

Evaluation of a serological test system for the diagnosis of natural echinococcus granulosus infection in dogs using echinococcus granulosus protoscolex and oncosphere antigens. Australian Veterinary Journal 65(12): 369-373, 1988

Use of Echinococcus granulosus worm antigens for immunodiagnosis of Echinococcus granulosus infection in dogs. Veterinary Parasitology 45(1-2): 89-100, 1992

Experimental study of the resistance of cattle and sheep to infection with echinococcus granulosus of porcine origin. Veterinarski Arhiv 56(1): 7-11, 1986

Immunoglobulin profiles in a murine intermediate host model of resistance for Echinococcus granulosus infection. Parasite Immunology 25(3): 161-168, 2003

Use of Echinococcus granulosus worm antigens for immunodiagnosis of E. granulosus infection in dogs. Veterinary Parasitology 45(1/2): 89-100, 1992

Identification of protein components of Echinococcus granulosus protoscolex antigens for specific serodiagnosis of E. granulosus infection in dogs. Parasite Immunology 11(3): 279-291, 1989

Susceptibility and resistance to Echinococcus granulosus infection: Associations between mouse strains and early peritoneal immune responses. Immunobiology 221(3): 418-426, 2016

Morphological and molecular characteristics of Echinococcus multilocularis and Echinococcus granulosus mixed infection in a dog from Xinjiang, China. Veterinary Parasitology 139(1-3): 244-248, 2006

Evaluation of a serological test system for the diagnosis of natural Echinococcus granulosus infection in dogs using E. granulosus protoscolex and oncosphere antigens. Australian Veterinary Journal 65(12): 369-373, 1988