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Trypanosoma rhodesiense: chemical and immunological characterization of variant-specific surface coat glycoproteins

Trypanosoma rhodesiense: chemical and immunological characterization of variant-specific surface coat glycoproteins

Molecular and Biochemical Parasitology 34: 227-238

Soluble surface coat glycoproteins were purified by concanavalin A affinity chromatography from variant populations of Trypanosoma rhodesiense (Wellcome strain). Each variant yielded a glycoprotein consisting of a single polypeptide chain. The apparent molecular weights of the different glycoproteins ranged from 58 000 to 67 000. Charge heterogeneity analyses resolved from 1 to 3 closely spaced components with isoelectric points that were considerably different from variant to variant.

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Accession: 001025743

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PMID: 6168907

DOI: 10.1016/0166-6851(81)90054-2

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