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Variations of urinary melatonin excretion in humans during the first 30 years of life



Variations of urinary melatonin excretion in humans during the first 30 years of life



Clinica Chimica Acta 110(1): 77-82



Urinary melatonin variation in humans were demonstrated to be a function of age. A radioimmunological assay was used. The values obtained, expressed as nmol x 24 h-1 x kg-1, progressively decreased from birth onwards, with a more accentuated and momentary inflection at the moment of the genital crisis in newborns and at puberty. The results obtained concern only melatonin and not its metabolites, as a result of the high specificity of the antibodies employed.

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Accession: 001030805

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PMID: 7214717

DOI: 10.1016/0009-8981(81)90303-x


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