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A model of L(+)-lactate metabolism in normal man



A model of L(+)-lactate metabolism in normal man



Annals of Nutrition & Metabolism 26(4): 254-263



Mathematical models were used to study the elimination of L(+)-lactate during and after an intravenous load of unlabelled sodium L(+)-lactate in 20 normal subjects after a meal. Clearance of L(+)-lactate from blood was 17.9 plus or minus 1.1 ml/kg bodyweight min and the endogenous production rate of L(+)-lactate at rest was 1.38 plus or minus 0.16 mol/70 kg 24 h. Clearance and production were unchanged after 36 h without food in 4 subjects.

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Accession: 001038532

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PMID: 7137947

DOI: 10.1159/000176571



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