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Characterisation of two highly oncogenic strains of Marek's disease virus

, : Characterisation of two highly oncogenic strains of Marek's disease virus. Avian Pathology 11(4): 593-605

The RB-1B and ALA-8 strains of Marek's disease (MD) virus, which were isolated from chickens with MD and which had been vaccinated with the herpesvirus of turkeys (HVT), were evaluated for their oncogenic potential in genetically susceptible (P-line) and resistant (N-line, PDRC) chickens. RB-1B and ALA-8 were both highly oncogenic, causing a high prevalence of MD in both susceptible and resistant birds. Vaccination of P-line birds with SB-1 or HVT did not protect satisfactorily against RB-1B.

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Accession: 001053136

PMID: 18770225

DOI: 10.1080/03079458208436134

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