EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Chemiluminescence response of peritoneal macrophages to parasitized erythrocytes and lysed erythrocytes from Plasmodium berghei-infected mice


Infection and Immunity 37(2): 800-804
Chemiluminescence response of peritoneal macrophages to parasitized erythrocytes and lysed erythrocytes from Plasmodium berghei-infected mice
The chemiluminescence response of normal mouse peritoneal macrophages to parasitized erythrocytes isolated from mice 3 weeks after infection with Plasmodium berghei was examined. Only 4 of 12 animals showed positive responses, whereas 8 showed negative responses. Photomicrographs revealed that only in chemiluminescence-positive animals were parasitized erythrocytes attached to or phagocytized by macrophages. When lysed parasitized-erythrocyte cell suspensions were added to the peritoneal macrophages, chemiluminescence could be induced in all cases. The response was enhanced remarkably by the addition of very small amounts of immune serum. Normal macrophages activated in vitro by supernatant from antigen-stimulated spleen cells from immune mice showed much higher parasite-induced chemiluminescence responses than did nonactivated macrophages, especially in the presence of immune serum.


Accession: 001053985

PMID: 6749686



Related references

Studies on the phagocytosis of parasitized erythrocytes from mice experimentally infected with plasmodium berghei by mouse peritoneal macrophages. Research Bulletin of Obihiro University Series I 10(2): 401-406, 1977

Suppression of the immune response to heterologous erythrocytes in mice infected with Plasmodium berghei berghei. Transactions of the Royal Society of Tropical Medicine and Hygiene 66(1): 5-6, 1972

Separation of parasitized erythrocytes from Plasmodium berghei infected mouse blood. Transactions of the Royal Society of Tropical Medicine and Hygiene 71(3): 267-268, 1977

Separation of parasitized erythrocytes from Plasmodium berghei infected mouse blood. Transactions of the Royal Society of Tropical Medicine and Hygiene 71(3): 267-268, 1977

Myelin-like forms of erythrocytes, monocytes (macrophages) and neutrophilic granulocytes in mice infected with Plasmodium berghei. Annales Pharmaceutiques Francaises 37(7/8): 275-284, 1979

Murine plasmodium 1. separation of merozoites and parasitized erythrocytes from mouse blood infected with plasmodium berghei by means of discontinuous gradients. Japanese Journal of Parasitology 32(2): 99-108, 1983

Destruction of parasitized erythrocytes by macrophages activated during malaria b abstract mouse plasmodium berghei. Bacteriological Proceedings 69: 84-85, 1969

Studies on murine Plasmodium 1. Separation of merozoites and parasitized erythrocytes from the mouse blood infected with Plasmodium berghei by means of siscontinuous gradients. Japanese Journal of Parasitology, 322: 99-108, 1983

Studies on murine Plasmodium. I. Separation of merozoites and parasitized erythrocytes from the mouse blood infected with Plasmodium berghei by means of discontinuous gradients.. Japanese journal of parasitology 32(2): 99-10829-38, 1983

Glutathione metabolism of Plasmodium berghei parasitized erythrocytes in mice. Indian Journal of Malariology 19(2): 109-113, 1982