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Effects of physical training on glucose tolerance and insulin response in diabetics



Effects of physical training on glucose tolerance and insulin response in diabetics



Osaka City Medical Journal 28(1): 1-8



The effects of 6 mo. of physical training on glucose tolerance and IRI [immunoreactive insulin] response to oral glucose load were studied in non-insulin dependent diabetic patients with fasting hyperglycemia. The reduction of body weight in diabetics treated with mild caloric restriction and physical training (training group, n = 10) was significantly greater than in those followed with mild caloric restriction alone during the same period as controls (sedentary group, n = 15). The significant improvement of glucose tolerance was observed both in the sedentary group and the training group, but significant increase of IRI response was observed only in the training group. No significant change in specific insulin binding to erythrocytes was observed in the both groups during the program. Apparently the recovery of pancreatic .beta.-cell function may be promoted by physical training in non-insulin-dependent diabetics with fasting hyperglycemia and low insulin response.

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Accession: 001071820

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PMID: 6763179



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