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Hormonal and cellular interactions in follicular steroid biosynthesis by the sheep ovary



Hormonal and cellular interactions in follicular steroid biosynthesis by the sheep ovary



Journal of Reproduction and Fertility. Supplement 30: 143-154



The cAMP production by granulosa cells from the smallest follicles studied (1-3 mm diameter) was stimulated by FSH but not by HCG in in vitro cultures; this suggested that functional FSH receptors exist at this early stage of differentiation. Medium-sized follicles (4-6 mm) responded to both FSH and HCG. Granulosa cells were unable to synthesise androgens, but readily converted exogenous testosterone to oestradiol-17 beta.

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Accession: 001085501

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PMID: 6300384



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