+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn

+ Translate
+ Recently Requested

Hormonal changes in catabolic patients during parenteral nutrition



Hormonal changes in catabolic patients during parenteral nutrition



Scandinavian Journal of Clinical and Laboratory Investigation 42(1): 19-26



This study assesses the hormonal changes in 23 catabolic surgical patients during the three different regimens of parenteral nutrition: one with glucose, another with glucose and fat as energy sources, and a third one rich in amino acids. Before treatment, plasma insulin and cortisol concentrations, as well as daily urinary excretion of 17-oxogenic steroids and catecholamines, were normal. Plasma growth hormone concentration was close to normal. Plasma testosterone and daily urinary excretion of 17-oxosteroids were decreased. The response of plasma cortisol concentration to glucagon was impaired but the responses of insulin and growth hormone were close to normal. During the glucose regimen plasma insulin increased by 270% and plasma testosterone by 60%. There was a 55% decrease in plasma growth hormone concentration and a 31% rise in plasma cortisol concentration. The lipid regimen enhanced plasma insulin by 120%. During the amino acid regimen plasma insulin concentration was 150% higher, but plasma growth hormone concentration 45% lower than initially. The glucose and amino acid regimens augmented the response of insulin to glucagon by 180 and 50%, respectively, but decreased that of growth hormone by 59 and 80%, respectively. The lipid programme caused no significant change in the hormonal response to glucagon.

(PDF emailed within 0-6 h: $19.90)

Accession: 001085505

Download citation: RISBibTeXText

PMID: 6813942

DOI: 10.1080/00365518209168045



Related references

L-glutamine-enriched parenteral nutrition in catabolic patients. Clinical Nutrition 12(1): 65-66, 1993

Changes in nitrogen metabolism in catabolic patients given three different parenteral nutrition regimens. Acta Chirurgica Scandinavica 147(7): 519-524, 1981

Peripheral, visceral and body nitrogen balance of catabolic patients, without and with parenteral nutrition. Intensive Care Medicine 14(3): 212-216, 1988

Optimal amino acid requirements during total parenteral nutrition (TPN) in catabolic patients. Rivista Italiana di Nutrizione Parenterale ed Enterale 10(3): 256-259, 1992

Collagen breakdown products and n balance in catabolic patients receiving total parenteral nutrition. Clinical Research 39(2): 655A, 1991

Medium-chain triglycerides as part of total parenteral nutrition in acute catabolic patients. Rivista Italiana di Nutrizione Parenterale ed Enterale 13(2): 107-113, 1995

Effect of total parenteral nutrition on the zinc, copper, and manganese status of patients with catabolic disease. Scandinavian Journal of Gastroenterology 21(4): 421-427, 1986

Parenteral nutrition including amino acids fails to increase creatinine clearance in catabolic patients. Scandinavian Journal of Clinical and Laboratory Investigation 49(5): 427-430, 1989

Protein catabolic rate in patients with acute renal failure on continuous arteriovenous hemofiltration and total parenteral nutrition. Journal of the American Society of Nephrology 3(8): 1516-1521, 1993

Effect of parenteral nutrition on the blood levels of insulin, glucagon, growth hormone, thyroid hormones and cortisol in catabolic patients. Acta Chirurgica Scandinavica 148(4): 315-322, 1982

Hypoglycemia in noncritically ill patients receiving total parenteral nutrition: a multicenter study. (Study group on the problem of hyperglycemia in parenteral nutrition; Nutrition area of the Spanish Society of Endocrinology and Nutrition). Nutrition 31(1): 58-63, 2016

Central venous catheter infections in home parenteral nutrition patients: Outcomes from Sustain: American Society for Parenteral and Enteral Nutrition's National Patient Registry for Nutrition Care. American Journal of Infection Control 44(12): 1462-1468, 2016

Gallbladder contraction after hormonal manipulations in normal subjects and patients under total parenteral nutrition. Journal of the American College of Nutrition 11(1): 17-20, 1992

Indications for parenteral nutrition in post operative catabolic states. Meng, H David H. Law (edited By). Parenteral Nutrition. Proceedings Of An International Symposium, Vanderbilt University School Of Medicine, Nashville, Tennessee. Xix: Springfield, Ill., U.s.a. 13-39, 1970

Catabolic response and parenteral nutrition after simultaneous kidney-pancreas transplantation. Nutrition 8(4): 232-236, 1992