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Human apolipoprotein A-I and A-II metabolism

Human apolipoprotein A-I and A-II metabolism

Journal of Lipid Research 23(6): 850-862

The kinetics of the major apolipoproteins (apo) of plasma high-density lipoproteins (HDL), apoA-I and apoA-II, were examined in 44 individual tracer studies in 22 normal male and female subjects. After the intravenous injection of radioiodinated HDL, the specific radioactivity decay of apoA-I within HDL was significantly faster than that of apoA-II. The specific radioactivity decay of apoA-I within HDL when labelled on HDL or as apoA was almost identical.

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Accession: 001085878

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PMID: 6813411

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