+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Immunologic studies of human schistosomiasis. II. Interrelationship of serum and ascitic fluid histamine, IgE and total eosinophils in acute and chronic human schistosomiasis



Immunologic studies of human schistosomiasis. II. Interrelationship of serum and ascitic fluid histamine, IgE and total eosinophils in acute and chronic human schistosomiasis



Annals of Allergy 50(3): 190-194



Sera and ascitic fluid of 26 patients with acute and chronic schistosomiasis were studied for the determination of histamine levels, IgE and total eosinophil counts and their correlation with the clinical manifestations of the disease. Serum histamine levels were significantly increased in acute and chronically infected patients. Serum IgE levels were markedly increased in all patients with S. mansoni infection and S. haematobium infection and moderately elevated in chronic patients. Eosinophilia was found in 60% of patients with S. mansoni infection and in 83% with S. haematobium infection. Ascitic fluid analysis revealed the presence of IgE and high concentrations of histamine. There was also a significant positive correlation (p less than 0.01) between serum and ascitic fluid histamine levels, as well as to IgE levels. These results support the contention that histamine and other immune system components may play a role in the pathophysiology of different stages of schistosomiasis.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 001087076

Download citation: RISBibTeXText

PMID: 6829985


Related references

Immunologic studies of human schistosomiasis. I. Clinical and immunological findings in acute and chronic schistosomiasis. Annals of Allergy 50(3): 182-189, 1983

Electrophoretic serum protein studies in chronic human Manson's schistosomiasis. American Journal of Tropical Medicine and Hygiene 10: 530-536, 1961

Seric chemokines and chemokine receptors in eosinophils during acute human schistosomiasis mansoni. Memórias do Instituto Oswaldo Cruz 105(4): 380-386, 2010

Seric chemokines and chemokine receptors in eosinophils during acute human schistosomiasis mansoni. Memorias do Instituto Oswaldo Cruz 105(4): 380-386, 2010

IgE response and histamine release in chronic human schistosomiasis. Biomedicine & PharmacoTherapy 39(1): 32-35, 1985

Hepatitis B surface antigen in serum, ascitic fluid and saliva in advanced hepatosplenic schistosomiasis. Journal of the Egyptian Society of Parasitology 18(1): 247-252, 1988

Immunoglobulin e response and histamine release in chronic human schistosomiasis. Biomedicine & Pharmacotherapy 39(1): 32-35, 1985

Studies on schistosomiasis in western Kenya: II. Efficacy of praziquantel for treatment of schistosomiasis in persons coinfected with human immunodeficiency virus-1. American Journal of Tropical Medicine and Hygiene 59(2): 307-311, 1998

Immune responses during human schistosomiasis mansoni 11. immunologic status of patients with acute infections and after treatment. Journal of Immunology 135(3): 2121-2127, 1985

Serum protein pattern in ascitic and non-ascitic cases of hepatosplenic schistosomiasis. Egyptian journal of bilharziasisssued 1983 8(1-2): 11-20, 1981

Eosinophilia, activated eosinophils and human schistosomiasis. Journal of Cell Science 98: 265-270, 1991

On the eosinophils, IgE and ELISA values in human schistosomiasis. Journal of the Egyptian Society of Parasitology 10(1): 19-25, 1980

Discriminating acute from chronic human schistosomiasis mansoni. Acta Tropica 108(2-3): 229-233, 2008

Cytokine profile associated with chronic and acute human schistosomiasis mansoni. Memorias do Instituto Oswaldo Cruz 103(6): 561-568, 2008

Human schistosomiasis mansoni: immune responses during acute and chronic phases of the infection. Acta Tropica 108(2-3): 0-117, 2008