+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Effect of prior administration of suxamethonium on non-depolarising muscle relaxants in the dog

Research in Veterinary Science 36(1): 43-47

Effect of prior administration of suxamethonium on non-depolarising muscle relaxants in the dog

The depolarizing muscle relaxant suxamethonium (0.3 mg/kg) was administered to 6 dogs. At 50% return of the neuromuscular activity, as measured by the train-of-four technique, a non-depolarizing muscle relaxant was administered. Three drugs, alcuronium (0.1 mg/kg), gallamine (1.0 mg/kg) and pancuronium (0.06 mg/kg), were injected i.v. At the 50% return of neuromuscular activity, atropine and neostigmine were administered to reverse the neuromuscular block. The duration of action of the 3 non-depolarizing relaxants was reduced by the prior administration of suxamethonium.

(PDF 0-2 workdays service: $29.90)

Accession: 001189084

PMID: 6709976

Related references

Effect of prior administration of a non-depolarising muscle relaxant on the action of suxamethonium in the dog. Research in Veterinary Science 36(3): 348-353, 1984

The effect of non-depolarising muscle relaxants on cholinergic mechanisms in the isolated rabbit heart. Anaesthesia 27(2): 143-148, 1972

The Effect of Non-Depolarising Muscle Relaxants on Ocular Pulse Amplitude and Intraocular Pressure. Klinische Monatsblatter für Augenheilkunde 232(12): 1397-1401, 2016

Incidence of muscle pain after short-acting relaxants; a comparison between suxamethonium chloride and suxamethonium bromide. British Medical Journal 1(5126): 904-905, 1959

Reversing non-depolarising muscle relaxants. Anaesthesia 71(9): 1110-1111, 2016

Clinical pharmacokinetics of the non-depolarising muscle relaxants. Clinical Pharmacokinetics 6(1): 25-60, 1981

Investigation of fading responses induced by non-depolarising muscle relaxants in the evoked EMG of the gastrocnemius muscle of the cat. Acta Anaesthesiologica Scandinavica 43(6): 658-662, July, 1999

Mivacurium A comparison with other benzylisoquinolinium non-depolarising muscle relaxants. Journal of Drug Development 5(SUPPL 1): 1-5, 1993

Does halothane prolong the effect of short-acting muscle relaxants of the suxamethonium type?. Der Anaesthesist 10: 141-142, 1961

Pharmacological investigations of muscle relaxants as adjuvant in anesthesia II Influences on brain stem reticular formation by single administration of various muscle relaxants and by combined administration with anesthetics. 1964