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Effect of pyronaridine and three other antimalarials on gametocytes and sporogony of Plasmodium yoelii

, : Effect of pyronaridine and three other antimalarials on gametocytes and sporogony of Plasmodium yoelii. Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 2(1): 28-31

When P. yoelii gametocyte-carrying mice given pyronaridine 1200 mg base/kg (approximate LD50) were fed 2 to 12 h later to batches of Anopheles stephensi no effect was observed on the development of oocysts and infective sporozoites in the mosquitoes. Similar results were obtained in mosquitoes fed on mice medicated with chloroquine 600 mg base/kg (approximate LD50).

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Accession: 001189149

PMID: 6467538

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