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Suppression of humoral immunity and lymphocyte responsiveness during experimental Trypanosoma cruzi infections



Suppression of humoral immunity and lymphocyte responsiveness during experimental Trypanosoma cruzi infections



Revista do Instituto de Medicina Tropical de Sao Paulo 26(2): 67-77



C3H/He and C57B1/6 mice were inoculated with 500 T. cruzi trypomastigotes (Strain Y). During the acute phase, infected mice presented parasitaemia and enlargement of lymph nodes and spleen and intracellular parasites were observed in the heart. Examination of cells derived from spleen and lymph nodes showed increased numbers of IgM- and IgG-bearing cells.

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Accession: 001259471

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PMID: 6433431



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